Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 8/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433569 | 0.81 | PRMT6 (0.42) | LMNADHODH | |
| SCHEMBL13884262 | 0.80 | SLC2A1 (0.51) | CYP2D6SLC2A1CASR | |
| SCHEMBL19301097 | 0.80 | PRMT6 (0.37) | LMNACYP2D6DHODH | |
| SCHEMBL21107584 | 0.77 | LMNA (0.42) | LMNACYP2D6CASRADRB2DHODH | |
| SCHEMBL24590164 | 0.76 | — | — | |
| SCHEMBL10087162 | 0.76 | LMNA (0.61) | LMNACYP2D6CASRADRB2TRPA1 | |
| SCHEMBL27112902 | 0.74 | TP53 (0.39) | LMNADHODH | |
| SCHEMBL18067758 | 0.73 | TP53BP1 (0.47) | — | |
| SCHEMBL21799477 | 0.73 | PNMT (0.44) | CYP2D6 | |
| SCHEMBL3360295 | 0.73 | TAAR1 (0.50) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580451-B2 | Sulfonic esters of metal oxides and methods of their use | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-02-28 | — | — | US | disclosed |