Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181998 | 0.96 | THRB (0.37) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL17075532 | 0.93 | THRB (0.40) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL21547311 | 0.93 | THRB (0.35) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL4094910 | 0.93 | TSHR (0.43) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL28572695 | 0.93 | THRB (0.40) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL20460074 | 0.92 | THRB (0.34) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL472550 | 0.92 | ACHE (0.38) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL22663545 | 0.92 | THRB (0.34) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL10405560 | 0.92 | ACHE (0.38) | THRBTSHRHRH4HRH3ACHE | |
| SCHEMBL3132587 | 0.92 | ACHE (0.38) | THRBTSHRHRH4HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564282-B1 | CURABLE COMPOSITION FOR USE IN A HIGH TEMPERATURE PHOTOPOLYMERISATION METHOD ON A LITHOGRAPHY BASIS AND PROCESS FOR THE PREPARATION OF CROSS-LINKED POLYMERS THEREFROM | ALIGN TECHNOLOGY INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-9580441-B2 | Dental compositions based on polymerizable resins containing isosorbide | DENTSPLY INTERNATIONAL INC. (US) | 2017-02-28 | — | — | US | disclosed |