Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 13/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181998 | 0.96 | THRB (0.37) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL15959227 | 0.94 | TSHR (0.38) | TSHRACHEHRH4HRH3POLB | |
| SCHEMBL21547311 | 0.93 | THRB (0.35) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL28572695 | 0.93 | THRB (0.40) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL17075532 | 0.93 | THRB (0.40) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL18558149 | 0.93 | THRB (0.35) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL20460074 | 0.92 | THRB (0.34) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL472550 | 0.92 | ACHE (0.38) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL22663545 | 0.92 | THRB (0.34) | TSHRACHEHRH4HRH3THRB | |
| SCHEMBL3132587 | 0.92 | ACHE (0.38) | TSHRACHEHRH4HRH3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028254-B2 | Dental prosthetics comprising curable acrylate polymer compositions and methods of their use | SCIENTIFIC PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130302513-A1 | DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE | SCIENT PHARMACEUTICALS INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20090239969-A1 | DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE | SCIENTIFIC PHARMACEUTICALS, INC (US) | 2009-09-24 | — | — | US | disclosed |
| US-20060035997-A1 | Curable acrylate polymer compositions featuring improved flexural characteristics | SCIENTIFIC PHARMACEUTICALS, INC. | 2006-02-16 | — | — | US | disclosed |