Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405560 | 1.00 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL472550 | 1.00 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL181998 | 0.95 | THRB (0.37) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18558149 | 0.92 | THRB (0.35) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21547311 | 0.92 | THRB (0.35) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4094910 | 0.92 | TSHR (0.43) | ACHETHRBTSHRHRH4HRH3 | |
| SCHEMBL17075532 | 0.92 | THRB (0.40) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28572695 | 0.92 | THRB (0.40) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20460074 | 0.91 | THRB (0.34) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22663545 | 0.91 | THRB (0.34) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951894-B1 | Storage stable polymerizable compositions | DENTSPLY DETREY GMBH (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-6998111-B2 | Storage stable polymerizable compositions | DENTAPLY DETREY GMBH (DE) | 2006-02-14 | — | — | US | disclosed |
| US-20020176826-A1 | STORAGE STABLE POLYMERIZABLE COMPOSITIONS | KLEE DR JOACHIM E (DE) | 2002-11-28 | — | — | US | disclosed |
| US-5688883-A | CATALYTIC POLYMERIZATION OF ACRYLATES FOR DENTAL SEALS OR ADHESIVES | DENTSPLY GMBH (DE) | 1997-11-18 | — | — | US | disclosed |
| EP-0732098-A2 | Polymerizable composition | DENTSPLY DETREY GmbH (DE) | 1996-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020176826-A1 | STORAGE STABLE POLYMERIZABLE COMPOSITIONS | H1-0, GPX4, H1-10 | ACHE 2226/4885CHRNB2 3630/4885CHRNB4 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.