Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558126 | 0.93 | RAB9A (0.38) | GRM5NPC1RAB9ABCHEACHE | |
| SCHEMBL18558380 | 0.93 | NPC1 (0.42) | NPC1RAB9ABCHEACHEALPL | |
| SCHEMBL18558387 | 0.93 | RAF1 (0.41) | GRM5NPC1RAB9ABCHEACHE | |
| SCHEMBL18558596 | 0.92 | RAF1 (0.42) | GRM5RAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18558156 | 0.91 | MAPT (0.36) | GRM5BCHEACHEALPLCNR2 | |
| SCHEMBL18558388 | 0.90 | MAPT (0.39) | GRM5BCHEACHEALPLCNR2 | |
| SCHEMBL18558653 | 0.90 | IDO1 (0.39) | NPC1RAB9AALPLSLC6A2CHRNA1 | |
| SCHEMBL18557825 | 0.90 | ALPL (0.38) | GRM5BCHEACHEALPLCNR2 | |
| SCHEMBL18558394 | 0.88 | RAF1 (0.39) | BCHEACHEALPLCNR2RAF1 | |
| SCHEMBL18558029 | 0.84 | NPC1 (0.40) | NPC1RAB9ABCHEACHEALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |