Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048860 | 0.85 | MLYCD (0.53) | MLYCDNAAAL3MBTL1PPARGPPARA | |
| SCHEMBL6022530 | 0.81 | MLYCD (0.58) | MLYCDNAAAL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL6023358 | 0.80 | MLYCD (0.54) | MLYCDNAAAL3MBTL1PPARGPPARA | |
| SCHEMBL6721904 | 0.80 | MLYCD (0.54) | MLYCDNAAAL3MBTL1PPARGPPARA | |
| SCHEMBL5045562 | 0.79 | ALDH1A1 (0.47) | MLYCDNAAAL3MBTL1PPARGPPARA | |
| SCHEMBL5044168 | 0.79 | ALDH1A1 (0.47) | MLYCDNAAAL3MBTL1PPARGPPARA | |
| SCHEMBL28929298 | 0.79 | MLYCD (0.76) | MLYCDNAAAL3MBTL1EPHX2MEN1 | |
| SCHEMBL5046020 | 0.79 | PPARG (0.53) | PPARGPPARAEPHX2PPARDHDAC1 | |
| SCHEMBL13577932 | 0.78 | MLYCD (0.73) | MLYCDNAAAL3MBTL1EPHX2MEN1 | |
| SCHEMBL5039932 | 0.78 | MLYCD (0.62) | MLYCDNAAAL3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |