Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565367

SCHEMBL18565367

SCHEMBL18565367

Cn1c2ccccc2c2cccc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALKBH5 Q6P6C2 1/20 0.41
▸ FTO Q9C0B1 1/20 0.41
▸ HSP90AA1 P07900 1/20 0.38
▸ IDO1 P14902 1/20 0.38
▸ GPR3 P46089 1/20 0.36
▸ HSD17B10 Q99714 2/20 0.35
▸ KDM4E B2RXH2 4/20 0.34
▸ MAPT P10636 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ HPGD P15428 2/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ ESR2 Q92731 1/20 0.33
▸ PSEN1 P49768 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565370 0.92 ALKBH5 (0.45) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22706085 0.89 ALKBH5 (0.36) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL18565402 0.89 MAOB (0.32) ALKBH5FTOKDM4EMAPTMEN1
SCHEMBL18565480 0.86 ALKBH5 (0.33) ALKBH5FTOHSP90AA1IDO1HSD17B10
SCHEMBL18565466 0.86 KDM4E (0.33) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL18565379 0.85 GPR3 (0.36) GPR3HSD17B10KDM4EMAPTMEN1
SCHEMBL18565438 0.85 TLR4 (0.32) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL13433005 0.85 KDM4E (0.42) GPR3HSD17B10KDM4EMAPTMEN1
SCHEMBL18565373 0.85 RXRA (0.47) GPR3HSD17B10KDM4EMAPTMEN1
SCHEMBL18565365 0.84 ALKBH5 (0.44) ALKBH5FTOHSP90AA1IDO1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885HSP90AA1 4595/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885HSP90AA1 4595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.