Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565370

SCHEMBL18565370

SCHEMBL18565370

Cn1c2ccccc2c2cccc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALKBH5 Q6P6C2 1/20 0.45
▸ FTO Q9C0B1 1/20 0.45
▸ HSP90AA1 P07900 1/20 0.41
▸ IDO1 P14902 1/20 0.41
▸ GPR3 P46089 1/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ HSD17B10 Q99714 3/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ PDK2 Q15119 6/20 0.35
▸ HPGD P15428 3/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ RET P07949 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565367 0.92 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL18565365 0.88 ALKBH5 (0.44) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL18565395 0.87 LMNA (0.34) ALKBH5FTOHSP90AA1IDO1KDM4E
SCHEMBL18565481 0.85 ALKBH5 (0.35) ALKBH5FTOHSP90AA1IDO1HSD17B10
SCHEMBL18565469 0.84 PDK2 (0.33) PDK2
SCHEMBL18565378 0.84 GPR3 (0.40) GPR3L3MBTL1HSD17B10KDM4EMAPT
SCHEMBL13433119 0.83 GPR3 (0.46) GPR3L3MBTL1HSD17B10KDM4EMAPT
SCHEMBL18565368 0.83 RXRA (0.48) HSP90AA1IDO1GPR3L3MBTL1HSD17B10
SCHEMBL17125533 0.83 GPR3 (0.46) GPR3L3MBTL1HSD17B10KDM4EMAPT
SCHEMBL18565435 0.83 KDM4E (0.32) KDM4EMAPTPDK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885HSP90AA1 4595/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885HSP90AA1 4595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.