Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673567 | 0.85 | HTT (0.44) | CYP4F2CYP4A11HTTKDM4EHSD17B10 | |
| SCHEMBL24202214 | 0.82 | HTT (0.45) | CYP4F2CYP4A11HTTKDM4EHSD17B10 | |
| SCHEMBL1974691 | 0.82 | HTT (0.45) | CYP4F2CYP4A11HTTKDM4EHSD17B10 | |
| SCHEMBL28717635 | 0.81 | THRB (0.45) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL15463122 | 0.81 | HTT (0.44) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL5034651 | 0.79 | HMGB1 (0.51) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL12445342 | 0.79 | ALDH1A1 (0.44) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL12392570 | 0.79 | TUBB4A (0.43) | CYP4F2CYP4A11HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL14384031 | 0.79 | ALOX15 (0.41) | CYP4F2CYP4A11KDM4EMAPTGAA | |
| SCHEMBL21790823 | 0.79 | HTT (0.43) | CYP4F2CYP4A11HTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536336-B2 | Prodrug compounds useful as cannabinoid ligands | ABBVIE INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-7989554-B2 | Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid | ENZON PHARMACEUTICALS, INC. (US) | 2011-08-02 | — | — | US | disclosed |
| WO-2011075522-A1 | PRODRUG COMPOUNDS USEFUL AS CANNABINOID LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20110144165-A1 | PRODRUG COMPOUNDS USEFUL AS CANNABINOID LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
| US-20070173615-A1 | High efficiency method of preparing polyalkylene oxide carboxylic acids | BELROSE PHARMA INC. | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144165-A1 | PRODRUG COMPOUNDS USEFUL AS CANNABINOID LIGANDS | CNR2, CNR1, OPRL1 | CYP4F2 835/4885CYP4A11 607/4885HTT 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.