SCHEMBL18567261

SCHEMBL18567261

CC(C)C(=O)OCC(C)(C)C[C@H](C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 1/20 0.40
KMT2A Q03164 2/20 0.39
CTSK P43235 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 2/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.37
ELANE P08246 1/20 0.36
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28838240 0.78 CTSL (0.47) L3MBTL1KMT2ACTSKTAAR1ALDH1A1
SCHEMBL22863307 0.77 CYP2C19 (0.47) RIPK1KMT2ATAAR1ALDH1A1TRPA1
SCHEMBL1171628 0.76 SMN1; SMN2 (0.46) L3MBTL1KMT2ATAAR1ALDH1A1TRPA1
SCHEMBL3503859 0.76 SMN1; SMN2 (0.46) L3MBTL1KMT2ATAAR1ALDH1A1TRPA1
SCHEMBL25970817 0.76 MAPK1 (0.59) KMT2AALDH1A1ELANENPC1LMNA
SCHEMBL18457189 0.75 L3MBTL1 (0.40) L3MBTL1ATMKMT2AALDH1A1MAPT
SCHEMBL18457121 0.75 L3MBTL1 (0.40) L3MBTL1ATMKMT2AALDH1A1MAPT
SCHEMBL20342289 0.74 TRPA1 (0.50) RIPK1TAAR1ALDH1A1TRPA1
SCHEMBL18567132 0.74 TRPA1 (0.50) RIPK1TAAR1ALDH1A1TRPA1
SCHEMBL954672 0.74 MMP8 (0.38) ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135663-A1 NOVEL COMPOUND, AND FLAVOR COMPOSITION CONTAINING SAID COMPOUND Takasago International Corporation (JP) 2017-03-01 EP disclosed