Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.44 |
| ▸ | VEGFA | P15692 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | STAMBP | O95630 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290548 | 0.84 | GAA (0.46) | EGLN1VEGFAFLT1EGLN3KDM4E | |
| SCHEMBL3980095 | 0.77 | OPRK1 (0.47) | KDM4EGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL290956 | 0.74 | KDM4E (0.53) | EGLN1VEGFAFLT1EGLN3KDM4E | |
| SCHEMBL23309599 | 0.72 | KDM4E (0.44) | EGLN1VEGFAFLT1EGLN3KDM4E | |
| SCHEMBL13954355 | 0.71 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2KMT2ACYP2C19LMNA | |
| SCHEMBL6032875 | 0.71 | AGBL2 (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15095650 | 0.71 | EGLN1 (0.46) | EGLN1VEGFAFLT1EGLN3KDM4E | |
| SCHEMBL17845037 | 0.70 | NNMT (0.42) | KDM4EKMT2A | |
| SCHEMBL12391060 | 0.69 | SMN1; SMN2 (0.51) | KDM4EGAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20587980 | 0.69 | KDM4E (0.46) | EGLN1VEGFAFLT1EGLN3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |