Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647464 | 0.77 | HPGD (0.48) | ALOX15PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL15360894 | 0.75 | VKORC1 (0.57) | ALOX15VKORC1PPARGKDM4EALDH1A1 | |
| SCHEMBL31140205 | 0.75 | MAOB (0.53) | PPARGKDM4EALDH1A1HPGDGAA | |
| SCHEMBL27476973 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL29799485 | 0.74 | MAOB (0.52) | KDM4EHPGDMAPTMAOBLMNA | |
| SCHEMBL2981579 | 0.74 | NPC1 (0.58) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL31544342 | 0.74 | KDM4E (0.59) | ALOX15PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL10520741 | 0.74 | ABCB1 (0.47) | PPARGKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL9533970 | 0.74 | PPARG (0.55) | PPARGKDM4EHPGDMAOBLMNA | |
| SCHEMBL26661262 | 0.73 | MAOB (0.51) | KDM4EHPGDMAPTMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041062-A1 | FILLERS FOR CHOCOLATE AND OTHER CONSUMABLES | Voyage Foods, Inc. | 2024-02-08 | — | — | US | disclosed |
| US-9382224-B2 | 7-acyloxychromen-4-one derivatives and the use thereof as self-tanning substances | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| EP-2665717-B1 | 7-ACYLOXY-CHROMEN-4-ONE DERIVATIVES AND THEIR USE AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2015-06-24 | — | — | EP | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| EP-1508327-B1 | Use of 5,7-dihydroxy-2-methylchromen-4-on for the care of the skin | MERCK PATENT GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| EP-2665717-A1 | 7-ACYLOXY-CHROMEN-4-ONE DERIVATIVES AND USE THEREOF AS SELF-TANNING SUBSTANCES | Merck Patent GmbH (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20130287716-A1 | 7-ACYLOXYCHROMEN-4-ONE DERIVATIVES AND THE USE THEREOF AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012097857-A1 | 7-ACYLOXY-CHROMEN-4-ONE DERIVATIVES AND USE THEREOF AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
| EP-1979337-B1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-1890672-B1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2007087956-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |
| US-20060292093-A1 | Chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2006-12-28 | — | — | US | disclosed |
| EP-1732913-A1 | CHROMONE COMPLEXES | MERCK PATENT GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006128562-A1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006094601-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | WO | disclosed |
| EP-1656364-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005097772-A1 | CHROMONE COMPLEXES | MERCK PATENT GMBH (DE) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005019197-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043398-A1 | Use of chromen-4-one derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287716-A1 | 7-ACYLOXYCHROMEN-4-ONE DERIVATIVES AND THE USE THEREOF AS SELF-TANNING SUBSTANCES | TYR, CYP7B1, CYP46A1 | ALOX15 463/4885VKORC1 478/4885PPARG 717/4885 |
| US-20050043398-A1 | Use of chromen-4-one derivatives | CYP8B1, CYP7B1, CYP2R1 | ALOX15 994/4885VKORC1 49/4885PPARG 1832/4885 |
| US-20060292093-A1 | Chromen-4-one derivatives | TYR, XPA, CYP19A1 | ALOX15 570/4885VKORC1 90/4885PPARG 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.