Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 4/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015574 | 0.87 | LDHA (0.52) | LDHAHPGDSHSD17B1HSD17B2FEN1 | |
| SCHEMBL19933578 | 0.87 | LDHA (0.52) | LDHAHPGDSHSD17B1HSD17B2FEN1 | |
| SCHEMBL23239876 | 0.86 | GRM5 (0.44) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL21721920 | 0.85 | LDHA (0.50) | LDHAHPGDSHSD17B1HSD17B2FEN1 | |
| SCHEMBL19794431 | 0.85 | LDHA (0.50) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL18015495 | 0.85 | LDHA (0.50) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL19794370 | 0.85 | LDHA (0.50) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL21125931 | 0.84 | HSD17B1 (0.56) | LDHAHPGDSHSD17B1HSD17B2FEN1 | |
| SCHEMBL19801366 | 0.83 | CLK4 (0.46) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL19933728 | 0.82 | LDHA (0.47) | LDHAHPGDSHSD17B1HSD17B2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11031562-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-08 | — | — | US | disclosed |
| WO-2017032439-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11031562-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | GABRG2 2032/4885GABRB3 1804/4885GABRA5 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.