Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794509 | 0.91 | CLK4 (0.39) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL19794470 | 0.87 | CLK4 (0.47) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL21202954 | 0.87 | CLK4 (0.47) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL19794490 | 0.86 | MEN1 (0.49) | MEN1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL19794497 | 0.85 | HSD17B1 (0.43) | MEN1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL27453697 | 0.84 | ALDH1A3 (0.49) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL27453360 | 0.83 | CYP1A2 (0.52) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL27453614 | 0.83 | CYP1A2 (0.52) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL27453367 | 0.83 | CYP1A2 (0.52) | CLK4CYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL18573258 | 0.83 | GABRG2 (0.46) | MEN1ALDH1A1KMT2AGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | CLK4 1837/4885CYP1A2 4170/4885MEN1 2821/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | CLK4 2671/4885CYP1A2 3140/4885MEN1 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.