Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | TDO2 | P48775 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647340 | 0.83 | PIM1 (0.50) | BACE1IDO1TDO2DYRK1ALDHA | |
| SCHEMBL5653453 | 0.80 | NPC1 (0.50) | IDO1TDO2DYRK1ALDHANPC1 | |
| SCHEMBL29106079 | 0.77 | LDHA (0.63) | IDO1TDO2LDHAHPGDALDH1A1 | |
| SCHEMBL1754202 | 0.77 | BACE1 (1.00) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL15646569 | 0.76 | MAPT (0.43) | IDO1TDO2LDHAALDH1A1NPC1 | |
| SCHEMBL18573282 | 0.76 | IDO1 (0.49) | IDO1TDO2LDHAHPGDALDH1A1 | |
| SCHEMBL21202845 | 0.75 | NPC1 (0.46) | IDO1TDO2DYRK1ALDHANPC1 | |
| SCHEMBL30480541 | 0.75 | LDHA (0.56) | IDO1TDO2DYRK1ALDHAALDH1A1 | |
| SCHEMBL13299607 | 0.75 | LDHA (0.56) | IDO1TDO2DYRK1ALDHAALDH1A1 | |
| SCHEMBL19781098 | 0.75 | MAPK1 (0.46) | IDO1TDO2DYRK1ALDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11031562-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-08 | — | — | US | disclosed |
| EP-3484868-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20190315787-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
| WO-2018011186-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | WO | disclosed |
| WO-2017032439-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315787-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | BACE1 2970/4885IDO1 2783/4885TDO2 2543/4885 |
| US-11031562-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | BACE1 2646/4885IDO1 2752/4885TDO2 2779/4885 |
| US-11713332-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | BACE1 2970/4885IDO1 2783/4885TDO2 2543/4885 |
| US-20230322826-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | BACE1 2970/4885IDO1 2783/4885TDO2 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.