Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219026 | 0.81 | GABRG2 (0.50) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL5827038 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL23702985 | 0.79 | CYP11B1 (0.54) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL7213782 | 0.79 | NPSR1 (0.53) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL4072388 | 0.76 | LDHA (0.53) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL7259682 | 0.76 | NPSR1 (0.54) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL18573286 | 0.76 | BACE1 (0.60) | IDO1TDO2ALDH1A1TDP1NPC1 | |
| SCHEMBL18573226 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13312281 | 0.73 | LDHA (0.50) | ALDH1A1NPSR1TDP1KDM4ENPC1 | |
| SCHEMBL4075302 | 0.73 | KDR (0.45) | IDO1TDO2ALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11031562-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-08 | — | — | US | disclosed |
| EP-3484868-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20190315787-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
| WO-2017032439-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315787-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | IDO1 2783/4885TDO2 2543/4885ALDH1A1 3754/4885 |
| US-11031562-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | IDO1 2752/4885TDO2 2779/4885ALDH1A1 3727/4885 |
| US-11713332-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | IDO1 2783/4885TDO2 2543/4885ALDH1A1 3754/4885 |
| US-20230322826-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | IDO1 2783/4885TDO2 2543/4885ALDH1A1 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.