Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16243409 | 0.88 | PTGES (0.35) | PTGESP2RX7HSD11B1LMNA | |
| SCHEMBL15492050 | 0.88 | PTGES (0.35) | PTGESP2RX7HSD11B1LMNA | |
| SCHEMBL14234100 | 0.83 | PTGES (0.38) | PTGESP2RX7TP53MAPT | |
| SCHEMBL16888428 | 0.83 | CA1 (0.36) | P2RX7HSD11B1TP53LMNAMAPT | |
| SCHEMBL12069085 | 0.82 | PTGES (0.36) | PTGESP2RX7TP53 | |
| SCHEMBL979491 | 0.81 | HSD11B1 (0.35) | P2RX7HSD11B1TP53LMNA | |
| SCHEMBL1858374 | 0.81 | — | — | |
| SCHEMBL980955 | 0.79 | HSD11B1 (0.35) | P2RX7HSD11B1TP53LMNA | |
| SCHEMBL983573 | 0.79 | ALDH1A1 (0.35) | P2RX7HSD11B1TP53LMNA | |
| SCHEMBL12948804 | 0.79 | ALDH1A1 (0.37) | P2RX7HSD11B1TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242283-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7947715-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | HCRTR1, HAX1, CHRM1 | PTGES 4793/4885P2RX7 155/4885HSD11B1 581/4885 |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | HCRTR1, CBR1, CHRM1 | PTGES 4751/4885P2RX7 244/4885HSD11B1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.