Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864283 | 0.86 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTCA12CA9 | |
| SCHEMBL22517147 | 0.84 | CA12 (0.40) | ALDH1A1SMN1; SMN2HSD11B1CA1CA2 | |
| SCHEMBL9986889 | 0.84 | KMT2A (0.46) | ALDH1A1SMN1; SMN2RAB9AHSD11B1MMP13 | |
| SCHEMBL28034923 | 0.84 | HSD11B1 (0.56) | ALDH1A1SMN1; SMN2HSD11B1MMP13KMT2A | |
| SCHEMBL1858895 | 0.84 | HSD11B1 (0.39) | ALDH1A1HSD11B1MMP13CA1CA2 | |
| SCHEMBL24723850 | 0.83 | CA12 (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1RECQL | |
| SCHEMBL31036586 | 0.82 | MMP13 (0.35) | ALDH1A1SMN1; SMN2HSD11B1MMP13CA1 | |
| SCHEMBL1860213 | 0.82 | ATM (0.38) | ALDH1A1SMN1; SMN2RAB9AHSD11B1MMP13 | |
| SCHEMBL14561944 | 0.81 | PTGS2 (0.46) | SMN1; SMN2RAB9ACA1CA2LMNA | |
| SCHEMBL24723852 | 0.81 | NR1I2 (0.40) | ALDH1A1SMN1; SMN2HSD11B1MMP13CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | AKR1C3, TPD52L2, HCCS | ALDH1A1 198/4885SMN1; SMN2 2869/4885RAB9A 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.