SCHEMBL185807

SCHEMBL185807

C=CC(=O)NC.CC(C)CS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
TGM2 P21980 2/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28875146 0.87 TSHR (0.39) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL25186942 0.84 TSHR (0.64) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL38654858 0.82 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27471616 0.82 ZDHHC20 (0.44) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL30357050 0.81 TSHR (0.37) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28523135 0.80 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylic Acid SCHEMBL21874408 0.80 LMNA (0.43) TSHRALDH1A1
Sulfuric Acid SCHEMBL27873789 0.80 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27469666 0.80 TGM2 (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylamide SCHEMBL6835393 0.79 TSHR (0.46) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866908-B A kind of preparation process of block of glass wool melamine modified phenolic resin 王珍丽 2018-10-12 CN claimed
CN-106866908-A A kind of preparation technology of block of glass wool melamine modified phenolic resin 孟红琳 2017-06-20 CN claimed
CN-101652326-B Method for the treatment with reverse osmosis membrane KURITA WATER IND LTD JP 2012-07-04 CN claimed
CN-101501077-B Method for producing polymer microparticles TOAGOSEI CO LTD 2011-09-07 CN claimed
CN-101652326-A Method for the treatment with reverse osmosis membrane KURITA WATER IND LTD JP 2010-02-17 CN claimed
CN-101501077-A Method for producing polymer microparticles TOAGOSEI CO LTD (JP) 2009-08-05 CN claimed
CN-1829435-A Seed coating composition, coated seed, and coating method SHOWA DENKO KK (JP) 2006-09-06 CN claimed
CN-110431205-A Adherence stacked film and structural body MITSUI CHEMICALS TOHCELLO INC 2019-11-08 CN disclosed
CN-104428331-B Active energy beam polymer resin composition and the laminated body for using the resin combination 东洋油墨SC控股株式会社 2019-02-15 CN disclosed
CN-109195643-A Lubricant coating for medical device 舒尔默迪克斯公司 2019-01-11 CN disclosed
CN-108883490-A The manufacturing method of conjugant 日东电工株式会社 2018-11-23 CN disclosed
CN-108020876-A polarizer 日东电工株式会社 2018-05-11 CN disclosed
CN-108020877-A polarizer 日东电工株式会社 2018-05-11 CN disclosed
CN-1789366-A Polishing composition for glass substrate KAO CORP (JP) 2006-06-21 CN disclosed
CN-1185267-C Dispersing stabilizing agent for suspension polymerization of vinyl compound KURARAY CO (JP) 2005-01-19 CN disclosed
CN-1175059-C Covering layer with easily removed attachments and using method thereof 日立马库塞鲁株式会社 2004-11-10 CN disclosed
CN-1412209-A Dispersing stabilizing agent for suspension polymerization of vinyl compound KURARAY CO (JP) 2003-04-23 CN disclosed
CN-1098386-C Fiber sizing agent KURARAY CO (JP) 2003-01-08 CN disclosed
CN-1194659-A Coating facilitating removal of adherent matter and method of using the same HITACHI MAXELL (JP) 1998-09-30 CN disclosed
CN-1171467-A Fiber sizing agent KURARAY CO (JP) 1998-01-28 CN disclosed