Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26167592 | 0.73 | HTR3A (0.43) | TNKSPARP1TNKS2ALDH1A1HTR3A | |
| SCHEMBL20888978 | 0.72 | TNKS (0.44) | TNKSPARP1TNKS2FABP3FABP4 | |
| SCHEMBL18554706 | 0.70 | TNKS (0.36) | TNKSPARP1TNKS2NPFFR1NPFFR2 | |
| SCHEMBL31228686 | 0.70 | TNKS (0.36) | TNKSPARP1TNKS2NPFFR1NPFFR2 | |
| SCHEMBL10018550 | 0.68 | DHODH (0.60) | FABP3FABP4ALDH1A1PTGESALOX5 | |
| SCHEMBL9494551 | 0.66 | PTGES (0.42) | FABP3FABP4ALDH1A1GAAPTGES | |
| SCHEMBL2709700 | 0.65 | NT5E (0.70) | ALDH1A1GAAHPGDHSD17B10DHODH | |
| SCHEMBL9493144 | 0.65 | NT5E (0.51) | PARP1ALDH1A1PTGESALOX5CYP2C9 | |
| SCHEMBL30492143 | 0.65 | NT5E (0.70) | ALDH1A1GAAHPGDHSD17B10DHODH | |
| SCHEMBL11828378 | 0.65 | NT5E (0.51) | ALDH1A1GAAPTGESALOX5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400106-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | Aldeyra Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| US-20230174491-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
| US-20210347735-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2021-11-11 | — | — | US | disclosed |
| US-11046650-B2 | Deuterated compounds and uses thereof | ALDEYRA THERAPEUTICS, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200199075-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2020-06-25 | — | — | US | disclosed |
| US-10550085-B2 | Deuterated compounds and uses thereof | ALDEYRA THERAPEUTICS, INC. (US) | 2020-02-04 | — | — | US | disclosed |
| WO-2017035077-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347735-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDH1A2, SSB, DBH | TNKS 3071/4885PARP1 736/4885TNKS2 3729/4885 |
| US-10550085-B2 | Deuterated compounds and uses thereof | ALDH1A2, SSB, DBH | TNKS 3071/4885PARP1 736/4885TNKS2 3729/4885 |
| US-20200199075-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDH1A2, SSB, DBH | TNKS 3071/4885PARP1 736/4885TNKS2 3729/4885 |
| US-20230174491-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | ALDH1A2, SSB, DBH | TNKS 3071/4885PARP1 736/4885TNKS2 3729/4885 |
| US-11046650-B2 | Deuterated compounds and uses thereof | ALDH1A2, SSB, DBH | TNKS 3071/4885PARP1 736/4885TNKS2 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.