Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | PYGL | P06737 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18584854 | 0.93 | PYGL (0.54) | KCNMA1RORCSMN1; SMN2KDM4EMAPT | |
| SCHEMBL18584852 | 0.84 | MAPT (0.62) | KCNMA1RORCKDM4EMAPTPYGL | |
| SCHEMBL23879956 | 0.83 | MAPT (0.50) | KCNMA1RORCSMN1; SMN2KDM4EMAPT | |
| SCHEMBL18584727 | 0.80 | TDP1 (0.51) | SMN1; SMN2MAPTALDH1A1PKMTDP1 | |
| SCHEMBL18585003 | 0.79 | MAPT (0.46) | KCNMA1RORCSMN1; SMN2KDM4EMAPT | |
| SCHEMBL16592413 | 0.78 | KCNMA1 (0.78) | KCNMA1RORCSMN1; SMN2KDM4EMAPT | |
| SCHEMBL13265673 | 0.77 | KCNMA1 (0.56) | KCNMA1RORCMAPTALDH1A1PKM | |
| SCHEMBL18585211 | 0.76 | ALDH1A1 (0.62) | KCNMA1RORCKDM4EMAPTPYGL | |
| SCHEMBL23879977 | 0.76 | MAPT (0.50) | KCNMA1RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL29886218 | 0.74 | KCNMA1 (0.77) | KCNMA1RORCSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136301-B2 | Broad spectrum antiviral compounds and uses thereof | The Regents of the University of California, A California Corporation et al. (US) | 2021-10-05 | — | — | US | disclosed |
| US-11136301-B2 | Broad spectrum antiviral compounds and uses thereof | The Regents of the University of California, A California Corporation et al. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20180297963-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF MIAMI | 2018-10-18 | — | — | US | disclosed |
| WO-2017040693-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136301-B2 | Broad spectrum antiviral compounds and uses thereof | MAVS, EIF2AK2, ZC3HAV1 | KCNMA1 4844/4885RORC 2117/4885SMN1; SMN2 1952/4885 |
| US-20180297963-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS AND USES THEREOF | MAVS, EIF2AK2, ZC3HAV1 | KCNMA1 4844/4885RORC 2117/4885SMN1; SMN2 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.