Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590955 | 0.81 | GCK (0.46) | DAO | |
| SCHEMBL8533941 | 0.77 | DAO (0.41) | DAOATAD2KDM5AHRH4MAPT | |
| SCHEMBL586564 | 0.77 | CYP19A1 (0.40) | MAPTCNR1ALDH1A1KDM4E | |
| SCHEMBL585937 | 0.74 | CA2 (0.40) | DAOMAPTALDH1A1KDM4E | |
| SCHEMBL13469140 | 0.68 | ATAD2 (0.53) | DAOATAD2KDM5AHRH4MAPT | |
| SCHEMBL30053741 | 0.66 | KDM5A (0.50) | DAOATAD2KDM5AHRH4MAPT | |
| SCHEMBL22430460 | 0.66 | ATAD2 (0.50) | DAOATAD2KDM5AHRH4MAPT | |
| SCHEMBL18590951 | 0.64 | HTR6 (0.35) | MAPTALDH1A1KDM4E | |
| SCHEMBL23511480 | 0.64 | ATAD2 (0.47) | DAOATAD2KDM5AHRH4MAPT | |
| SCHEMBL18590950 | 0.63 | ATAD2 (0.42) | DAOATAD2HRH4MAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593108-B2 | Compounds and methods for antiviral treatment | PTC THERAPEUTICS, INC. (US) | 2017-03-14 | — | — | US | disclosed |