Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590949 | 0.81 | DAO (0.40) | DAO | |
| SCHEMBL586564 | 0.79 | CYP19A1 (0.40) | — | |
| SCHEMBL8536248 | 0.77 | GCK (0.44) | GCKDAORIPK1 | |
| SCHEMBL585937 | 0.76 | CA2 (0.40) | DAO | |
| SCHEMBL8533233 | 0.76 | GCK (0.47) | GCKDAORIPK1 | |
| SCHEMBL1960655 | 0.71 | GCK (0.52) | GCK | |
| SCHEMBL3823645 | 0.70 | HTR2A (0.51) | GCKRIPK1 | |
| SCHEMBL8135643 | 0.69 | RIPK1 (0.47) | GCKDAORIPK1 | |
| SCHEMBL18590951 | 0.68 | HTR6 (0.35) | GCK | |
| SCHEMBL2981817 | 0.68 | DAO (0.49) | GCKDAORIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593108-B2 | Compounds and methods for antiviral treatment | PTC THERAPEUTICS, INC. (US) | 2017-03-14 | — | — | US | disclosed |