Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595709 | 0.75 | NPSR1 (0.53) | KIF11NPSR1KMT2AKDM4ECASP3 | |
| SCHEMBL811160 | 0.75 | NPSR1 (0.53) | KIF11NPSR1KMT2AKDM4ECASP3 | |
| SCHEMBL2934747 | 0.74 | KIF11 (0.43) | KIF11NPSR1KMT2AKDM4EKDM1A | |
| SCHEMBL6033597 | 0.72 | CASP3 (0.45) | KIF11NOS3NOS2NPSR1KMT2A | |
| SCHEMBL28510482 | 0.71 | CYP11B1 (0.43) | KIF11NPSR1KMT2AKDM4EKDM1A | |
| SCHEMBL31114170 | 0.71 | CYP11B1 (0.43) | KIF11NPSR1KMT2AKDM4EKDM1A | |
| Ammonia Solution, Strong SCHEMBL1863056 | 0.70 | MAPT (0.40) | KIF11NOS3NOS2NPSR1KMT2A | |
| SCHEMBL27344645 | 0.70 | KIF11 (0.63) | KIF11NPSR1KMT2AKDM4ECASP3 | |
| SCHEMBL1862303 | 0.70 | KIF11 (0.41) | KIF11NPSR1KMT2AKDM4ECASP3 | |
| SCHEMBL10416583 | 0.70 | KMT2A (0.41) | KIF11NPSR1KMT2AKDM4EKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935702-B2 | Substituted biaryl quinolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2011-05-03 | — | — | US | disclosed |