Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18595310 | 1.00 | LMNA (0.38) | LMNAMAOASLC6A2PDCD4DAGLA | |
| SCHEMBL18595269 | 1.00 | LMNA (0.38) | LMNAMAOASLC6A2PDCD4DAGLA | |
| SCHEMBL18595308 | 0.98 | LMNA (0.38) | LMNAMAOASLC6A2PDCD4DAGLA | |
| SCHEMBL21679670 | 0.80 | CYP1A2 (0.45) | LMNAPDCD4DAGLACYP1A2 | |
| SCHEMBL9322761 | 0.78 | CYP1A2 (0.54) | LMNAMAOASLC6A2PKMCYP1A2 | |
| SCHEMBL2830202 | 0.78 | CYP1A2 (0.54) | LMNAMAOASLC6A2PKMCYP1A2 | |
| SCHEMBL5452024 | 0.74 | LMNA (0.45) | LMNAMAOASLC6A2PKMCYP1A2 | |
| SCHEMBL5450456 | 0.72 | — | — | |
| SCHEMBL24920072 | 0.72 | NAAA (0.36) | LMNAMAOAPDCD4DAGLACYP1A2 | |
| SCHEMBL2366099 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |