SCHEMBL18595396

SCHEMBL18595396

Cc1nc(Cc2ccccc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PDE2A O00408 1/20 0.39
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14589691 0.88 CALM1 (0.42) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL18595394 0.87 HTR6 (0.37) L3MBTL1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL18595393 0.83 L3MBTL1 (0.40) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL17358224 0.82 L3MBTL1 (0.49) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL17548980 0.80 ALDH1A1 (0.47) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL17486265 0.77 ALDH1A1 (0.44) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL17358223 0.75 ALDH1A1 (0.44) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL13520566 0.75 ALDH1A1 (0.41) ALDH1A1L3MBTL1MEN1KMT2APDE2A
SCHEMBL9080796 0.72 KDM4E (0.33)
SCHEMBL28647099 0.71 PDE2A (0.47) ALDH1A1L3MBTL1MEN1KMT2APDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9588426-B2 Negative photoresist and methods of preparing and using the same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-03-07 US disclosed