Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.38 |
| ▸ | MMP2 | P08253 | 8/20 | 0.38 |
| ▸ | MMP3 | P08254 | 7/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | STAT5B | P51692 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861012 | 0.95 | TP53 (0.37) | MMP13MMP2MMP3CTSSCTSK | |
| SCHEMBL1861139 | 0.91 | ALDH1A1 (0.36) | MMP13MMP2MMP3CTSSCTSK | |
| SCHEMBL1855155 | 0.86 | STAT5B (0.37) | MMP13MMP2MMP3CTSSCTSK | |
| SCHEMBL1855701 | 0.85 | MMP2 (0.41) | MMP2MMP3MMP9MMP1MMP8 | |
| SCHEMBL1855947 | 0.84 | MMP13 (0.41) | MMP13MMP2MMP3MMP9MMP1 | |
| SCHEMBL1860841 | 0.83 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1855996 | 0.83 | STAT5B (0.36) | MMP13MMP2MMP3MMP9MMP1 | |
| SCHEMBL1856124 | 0.81 | TP53 (0.41) | MMP2MMP3MMP9MMP1MMP8 | |
| SCHEMBL3465873 | 0.80 | MMP13 (0.42) | MMP13MMP2MMP3CTSSCTSK | |
| SCHEMBL1857571 | 0.80 | ALDH1A1 (0.39) | MMP13MMP2MMP3CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2011-05-05 | — | — | US | disclosed |
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | AKR1C3, TPD52L2, HCCS | MMP13 3116/4885MMP2 2326/4885MMP3 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.