Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918588 | 1.00 | AAK1 (0.30) | AAK1EPHX1 | |
| SCHEMBL8915468 | 1.00 | AAK1 (0.30) | AAK1EPHX1 | |
| SCHEMBL12943507 | 0.93 | MMP2 (0.37) | AAK1EPHX1 | |
| SCHEMBL20643834 | 0.93 | MMP2 (0.33) | AAK1EPHX1 | |
| SCHEMBL10072271 | 0.91 | MMP2 (0.39) | AAK1EPHX1 | |
| SCHEMBL15887502 | 0.91 | MMP2 (0.39) | AAK1EPHX1 | |
| SCHEMBL20643824 | 0.89 | AAK1 (0.36) | AAK1 | |
| SCHEMBL8918660 | 0.89 | AAK1 (0.36) | AAK1 | |
| SCHEMBL10150991 | 0.89 | AAK1 (0.36) | AAK1 | |
| SCHEMBL16705489 | 0.86 | ALOX15 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039754-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-10028937-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-20170157105-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028937-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | AAK1 2181/4885EPHX1 3100/4885 |
| US-20170157105-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | AAK1 2181/4885EPHX1 3100/4885 |
| US-10039754-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | AAK1 2181/4885EPHX1 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.