SCHEMBL1859707

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1856429	0.90	POLB (0.51)	POLBTDP1MMP2MMP9MMP8
	SCHEMBL1857400	0.89	POLB (0.49)	POLBTDP1MMP2MMP9MMP8
	SCHEMBL1860335	0.84	NR1H2 (0.42)	POLBMMP9ALDH1A1MMP1MMP3
	SCHEMBL1859940	0.83	GRIK1 (0.51)	POLBMMP2FOLH1CYP2C9CYP2C19
	SCHEMBL1857288	0.81	HTR6 (0.51)	ALDH1A1
	SCHEMBL1858600	0.80	GRIK1 (0.54)	POLBMMP2FOLH1CYP2C9CYP2C19
	SCHEMBL1865607	0.80	MAOA (0.49)	MMP2FOLH1MMP3
	SCHEMBL1861214	0.79	ALDH1A1 (0.39)	MMP2MMP9MMP8FOLH1ALDH1A1
	SCHEMBL1865669	0.79	FAAH (0.48)	MMP2FOLH1PDE4APDE4BPDE4C
	SCHEMBL12630230	0.79	ALDH1A1 (0.51)	POLBTDP1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.