Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18597914 | 0.90 | THRB (0.39) | FFAR1FFAR4THRBEPHX1 | |
| SCHEMBL18597930 | 0.87 | PTGER1 (0.54) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL7136 | 0.85 | FFAR1 (0.43) | FFAR1FFAR4THRATHRBPPARG | |
| SCHEMBL18597928 | 0.84 | LMNA (0.41) | EPHX1 | |
| SCHEMBL7135 | 0.84 | FFAR1 (0.46) | FFAR1FFAR4THRATHRBPPARG | |
| SCHEMBL7260 | 0.83 | PTGER1 (0.50) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL6615 | 0.80 | FFAR1 (0.50) | FFAR1FFAR4THRATHRBPPARG | |
| SCHEMBL18597994 | 0.78 | LPAR1 (0.48) | FFAR4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL18597925 | 0.77 | LPAR1 (0.43) | FFAR4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL14570 | 0.77 | FFAR1 (0.47) | FFAR1FFAR4PTGER1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-B1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |