Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585 | 0.92 | EPHX1 (0.42) | EPHX1RXRARXRBRXRG | |
| SCHEMBL7428 | 0.90 | EPHX1 (0.40) | FFAR1FFAR4EPHX1THRB | |
| SCHEMBL7577 | 0.88 | FFAR1 (0.43) | FFAR1FFAR4PPARD | |
| SCHEMBL18597716 | 0.85 | FFAR1 (0.48) | FFAR1FFAR4EPHX1THRATHRB | |
| SCHEMBL6871 | 0.85 | EPHX1 (0.40) | EPHX1THRB | |
| SCHEMBL6615 | 0.85 | FFAR1 (0.50) | FFAR1FFAR4MMETHRATHRB | |
| SCHEMBL2285 | 0.85 | LPAR1 (0.41) | EPHX1 | |
| SCHEMBL7135 | 0.82 | FFAR1 (0.46) | FFAR1FFAR4EPHX1MMETHRA | |
| SCHEMBL1679 | 0.80 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL7741 | 0.78 | CYP4F2 (0.39) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |