Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634171 | 0.83 | NFE2L2 (0.56) | TRPM8NFE2L2KMT2ACYP1A1CYP1A2 | |
| SCHEMBL27741087 | 0.74 | HSD11B1 (0.46) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21798669 | 0.74 | NFE2L2 (0.66) | TRPM8NFE2L2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL16274575 | 0.74 | HPGD (0.67) | TRPM8NFE2L2KMT2AABCB1L3MBTL1 | |
| SCHEMBL16274720 | 0.74 | HPGD (0.67) | TRPM8NFE2L2KMT2AABCB1L3MBTL1 | |
| SCHEMBL14190940 | 0.70 | KMT2A (0.61) | TRPM8NFE2L2KMT2ACYP1A1CYP1A2 | |
| SCHEMBL4382984 | 0.70 | KMT2A (0.61) | TRPM8NFE2L2KMT2ACYP1A1CYP1A2 | |
| SCHEMBL4393529 | 0.70 | NFE2L2 (0.59) | TRPM8NFE2L2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL457033 | 0.70 | NFE2L2 (0.79) | TRPM8NFE2L2KMT2ACYP1A1CYP1A2 | |
| SCHEMBL6776487 | 0.70 | NFE2L2 (0.79) | TRPM8NFE2L2KMT2ACYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810941-B1 | NOVEL PIPERINE DERIVATIVE AND USE THEREFOR | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIV (KR) | 2017-03-15 | — | — | EP | disclosed |