Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601625 | 0.83 | TRPM8 (0.51) | NFE2L2TRPM8ALOX5KMT2AMAOB | |
| SCHEMBL21798669 | 0.78 | NFE2L2 (0.66) | NFE2L2TRPM8ALOX5CYP1A1CYP1A2 | |
| SCHEMBL16274575 | 0.78 | HPGD (0.67) | NFE2L2TRPM8KMT2AABCB1L3MBTL1 | |
| SCHEMBL16274720 | 0.78 | HPGD (0.67) | NFE2L2TRPM8KMT2AABCB1L3MBTL1 | |
| SCHEMBL11554117 | 0.74 | NFE2L2 (0.66) | NFE2L2KMT2AMAOBNPC1RAB9A | |
| SCHEMBL11554121 | 0.74 | NFE2L2 (0.66) | NFE2L2KMT2AMAOBNPC1RAB9A | |
| SCHEMBL4393529 | 0.74 | NFE2L2 (0.59) | NFE2L2TRPM8ALOX5CYP1A1CYP1A2 | |
| SCHEMBL27732245 | 0.73 | NFE2L2 (0.77) | NFE2L2TRPM8ALOX5KMT2AMAOB | |
| SCHEMBL7422566 | 0.72 | NFE2L2 (0.56) | NFE2L2TRPM8ALOX5KMT2AMAOB | |
| SCHEMBL2744353 | 0.72 | NFE2L2 (1.00) | NFE2L2TRPM8ALOX5KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810941-B1 | NOVEL PIPERINE DERIVATIVE AND USE THEREFOR | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIV (KR) | 2017-03-15 | — | — | EP | disclosed |