Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082953 | 0.95 | ADH1A (0.42) | ADH1CADH1AALOX5LTA4H | |
| SCHEMBL11638870 | 0.92 | SLC6A2 (0.30) | ALOX5 | |
| SCHEMBL24379259 | 0.85 | SLC6A2 (0.40) | — | |
| SCHEMBL24079843 | 0.84 | MEN1 (0.33) | ADH1CADH1A | |
| SCHEMBL24080142 | 0.81 | LTA4H (0.36) | ADH1CADH1AALOX5LTA4H | |
| SCHEMBL9290239 | 0.81 | ADH1A (0.41) | ADH1CADH1A | |
| SCHEMBL614355 | 0.81 | — | — | |
| SCHEMBL12449085 | 0.79 | LTA4H (0.38) | ADH1CADH1AALOX5LTA4H | |
| SCHEMBL383574 | 0.78 | ADH1A (0.46) | ADH1CADH1ALTA4H | |
| SCHEMBL9289339 | 0.78 | ADH1A (0.46) | ADH1CADH1ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427425-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |