Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18602764 | 0.92 | ADH1C (0.35) | ALOX5 | |
| SCHEMBL13082953 | 0.88 | ADH1A (0.42) | SLC6A2SLC6A4ALOX5 | |
| SCHEMBL835196 | 0.80 | — | — | |
| SCHEMBL9862148 | 0.80 | ADH1C (0.33) | SLC6A2SLC6A4 | |
| SCHEMBL12599373 | 0.79 | NOS3 (0.31) | — | |
| SCHEMBL24079843 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL24379259 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL26773083 | 0.77 | — | — | |
| SCHEMBL12448946 | 0.77 | — | — | |
| SCHEMBL18155341 | 0.75 | ADH1A (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427425-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-4102890-A | HYPNOTIC, ANALGESIC, HYPOTENSIVE, CARDIOVASCULAR DEPRESSANTS, NEURO-MODULATORS | SCIENCE-UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1978-07-25 | — | — | US | disclosed |