SCHEMBL1860645

SCHEMBL1860645

CCOC(=O)C(Cc1ccc(NCCCN2CC(C)Oc3ccccc32)cc1)OCC.CCOC(Cc1ccc(NCCCN2CC(C)Oc3ccccc32)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.46
PPARA Q07869 15/20 0.46
PPARD Q03181 4/20 0.39
PTPRF P10586 1/20 0.37
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1865976 0.97 PPARG (0.41) PPARGPPARA
SCHEMBL1862230 0.96 PPARG (0.49) PPARGPPARAPPARDPTPRFPTPN2
SCHEMBL4822987 0.96 PPARG (0.49) PPARGPPARAPPARDPTPRFPTPN2
SCHEMBL4817522 0.95 PPARG (0.49) PPARGPPARAPPARDPTPRFPTPN2
SCHEMBL1870599 0.92 PPARG (0.39) PPARGPPARAPPARDPTPRFPTPN2
SCHEMBL14194982 0.90 MAPT (0.38) PPARGPPARA
SCHEMBL1863184 0.90 MAPT (0.38) PPARGPPARA
SCHEMBL1865902 0.90 PPARG (0.44) PPARGPPARAPPARDPTPRFPTPN2
SCHEMBL4817528 0.89 PPARG (0.42) PPARGPPARAPPARD
SCHEMBL1870590 0.87 PPARG (0.39) PPARGPPARAPPARDPTPRFPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110105748-A1 Novel beta-phenyl-alpha-oxysubstituted propionic derivatives: process for its preparation and their use in the preparation of pharmaceutically important compounds REDDY'S LABORATORIES INC. 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105748-A1 Novel beta-phenyl-alpha-oxysubstituted propionic derivatives: process for its preparation and their use in the preparation of pharmaceutically important compounds PCCA, ADRA1B, ADRA2B PPARG 994/4885PPARA 822/4885PPARD 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.