Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 3/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819725 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28831158 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28267019 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28267364 | 0.89 | PSMB5 (0.56) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL1023542 | 0.88 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL22103875 | 0.86 | RAB9A (0.76) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL24205749 | 0.86 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL24205750 | 0.86 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL9001595 | 0.86 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9AKDM4EHPGD | |
| SCHEMBL10289630 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2NPC1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180590-A | A method of Benzoheterocyclic compounds are quickly prepared using physical grinding method under room temperature solvent-free | 福建医科大学 | 2019-01-11 | — | — | CN | disclosed |
| US-20170066711-A1 | METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066711-A1 | METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND | AOX1, NOX4, NOXO1 | SMN1; SMN2 3015/4885NPC1 1680/4885RAB9A 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.