Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551998 | 0.73 | AXL (0.36) | MAPK1ALDH1A1GABRG2GABRB3GABRA5 | |
| SCHEMBL10806706 | 0.66 | CHEK1 (0.41) | L3MBTL1MAPK1METAP2NPSR1ALDH1A1 | |
| SCHEMBL5664674 | 0.64 | L3MBTL1 (0.39) | L3MBTL1MAPK1NPSR1ALDH1A1ADORA2A | |
| SCHEMBL1227720 | 0.63 | KMT2A (0.46) | L3MBTL1MAPK1NPSR1ALDH1A1TDP1 | |
| SCHEMBL12825464 | 0.63 | ALDH1A1 (0.46) | L3MBTL1MAPK1NPSR1ALDH1A1GABRG2 | |
| SCHEMBL7220037 | 0.63 | ADORA1 (0.49) | L3MBTL1MAPK1NPSR1ALDH1A1ADORA2A | |
| SCHEMBL6971354 | 0.63 | L3MBTL1 (0.38) | L3MBTL1MAPK1NPSR1ALDH1A1TDP1 | |
| SCHEMBL1146097 | 0.63 | CYP1A2 (0.57) | L3MBTL1NPSR1ALDH1A1TDP1GABRG2 | |
| SCHEMBL7213782 | 0.62 | NPSR1 (0.53) | L3MBTL1MAPK1NPSR1ALDH1A1TDP1 | |
| Bromide SCHEMBL20536256 | 0.61 | ALDH1A1 (0.51) | L3MBTL1MAPK1NPSR1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347097-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-18 | — | — | EP | claimed |
| WO-2017044434-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | WO | claimed |