Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.65 |
| ▸ | AXL | P30530 | 11/20 | 0.65 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 6/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 6/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779419 | 0.90 | MERTK (0.61) | MERTKAXLACVR1BMPR1BBMPR1A | |
| SCHEMBL18616315 | 0.80 | MERTK (0.60) | MERTKAXLACVR1BMPR1BBMPR1A | |
| SCHEMBL18581004 | 0.80 | AXL (1.00) | MERTKAXL | |
| SCHEMBL18611887 | 0.77 | MERTK (0.59) | MERTKAXLACVR1BMPR1BBMPR1A | |
| SCHEMBL18580395 | 0.73 | AXL (0.89) | MERTKAXL | |
| SCHEMBL18579601 | 0.73 | MERTK (1.00) | MERTKAXL | |
| SCHEMBL18615845 | 0.72 | AXL (0.62) | MERTKAXLACVR1BMPR1BBMPR1A | |
| SCHEMBL18612199 | 0.72 | L3MBTL3 (0.59) | MERTKAXLPIK3C3 | |
| SCHEMBL18616643 | 0.72 | AXL (0.66) | MERTKAXLACVR1BMPR1BBMPR1A | |
| SCHEMBL18616607 | 0.71 | MERTK (0.65) | MERTKAXLACVR1BMPR1BBMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |