Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IL18 | Q14116 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549960 | 0.83 | MEN1 (0.47) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL28662441 | 0.81 | PGR (0.49) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL10927383 | 0.81 | CYP19A1 (0.59) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL20357557 | 0.79 | MAPT (0.57) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL18615548 | 0.79 | MEN1 (0.44) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL28558177 | 0.77 | ALDH1A1 (0.53) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL28770468 | 0.76 | CYP19A1 (0.54) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL7073983 | 0.76 | CYP19A1 (0.54) | MEN1MAPTKMT2ACYP19A1KDM4E | |
| SCHEMBL11645604 | 0.75 | MAPK1 (0.56) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL10923033 | 0.74 | PDE4A (0.55) | MEN1MAPTKMT2ACYP19A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036405-A1 | COMPOUND HAVING PROTEIN TYROSINE PHOSPHATASE SHP-1 AGONIST ACTIVITY | 陈昆锋 | 2017-03-09 | — | — | WO | disclosed |