Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IL18 | Q14116 | 1/20 | 0.46 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549960 | 0.83 | MEN1 (0.47) | PGRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL18615547 | 0.81 | MEN1 (0.46) | PGRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL10927383 | 0.81 | CYP19A1 (0.59) | PGRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL378478 | 0.81 | CYP19A1 (0.63) | PGRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL14677816 | 0.79 | PGR (0.71) | PGRMEN1MAPTKMT2A | |
| SCHEMBL14678023 | 0.79 | NR1H4 (0.66) | PGRMAPK1MEN1MAPTRAB9A | |
| SCHEMBL20357557 | 0.79 | MAPT (0.57) | KDM4ELMNAPOLBMAPK1CYP19A1 | |
| SCHEMBL18615548 | 0.79 | MEN1 (0.44) | PGRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL30912302 | 0.77 | TSHR (0.59) | KDM4ECYP19A1MEN1MAPTKMT2A | |
| SCHEMBL28558177 | 0.77 | ALDH1A1 (0.53) | KDM4ELMNAPOLBMAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512002-A | Pyrazole amide compound containing azo structure and preparation and application thereof | 华东理工大学 | 2021-10-19 | — | — | CN | disclosed |