Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543139 | 1.00 | OPRD1 (0.47) | OPRD1KDM4CACHEESR1ESR2 | |
| SCHEMBL16543141 | 1.00 | OPRD1 (0.47) | OPRD1KDM4CACHEESR1ESR2 | |
| SCHEMBL14606247 | 0.90 | DRD2 (0.42) | OPRD1ACHEESR1ESR2 | |
| SCHEMBL13499147 | 0.87 | OPRD1 (0.47) | OPRD1ACHEESR1ESR2 | |
| SCHEMBL6330755 | 0.87 | ACHE (0.50) | OPRD1ACHE | |
| SCHEMBL8281689 | 0.87 | ACHE (0.50) | OPRD1ACHE | |
| Hydrochloric Acid SCHEMBL3171185 | 0.85 | ACHE (0.49) | OPRD1ACHE | |
| SCHEMBL1726880 | 0.83 | OPRD1 (0.45) | OPRD1ACHEESR1ESR2 | |
| SCHEMBL4517111 | 0.83 | OPRD1 (0.45) | OPRD1ACHEESR1ESR2 | |
| SCHEMBL1726878 | 0.83 | OPRD1 (0.45) | OPRD1ACHEESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |