SCHEMBL186164

SCHEMBL186164

CC(C)(CCCCCCCCCCC(C)(C)CC(=O)O)CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 1.00
CPT2 P23786 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
KDM4E B2RXH2 1/20 0.52
HMGCR P04035 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
CYP2C19 P33261 2/20 0.46
HIF1A Q16665 2/20 0.46
TSHR P16473 2/20 0.46
CYP2D6 P10635 1/20 0.46
BHMT Q93088 3/20 0.43
ACLY P53396 1/20 0.40
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TBXAS1 P24557 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5523390 1.00 FFAR1 (1.00) FFAR1CPT2TDP1KDM4EHMGCR
SCHEMBL8037883 1.00 FFAR1 (1.00) FFAR1CPT2TDP1KDM4EHMGCR
SCHEMBL1832938 1.00 FFAR1 (1.00) FFAR1CPT2TDP1KDM4EHMGCR
SCHEMBL1834211 1.00 FFAR1 (1.00) FFAR1CPT2TDP1KDM4EHMGCR
SCHEMBL14810357 0.91 TDP1 (0.83) FFAR1CPT2TDP1KDM4EADRA1A
SCHEMBL22748728 0.91 TDP1 (0.83) FFAR1CPT2TDP1TSHRALDH1A1
SCHEMBL742996 0.91 TDP1 (0.83) FFAR1CPT2TDP1TSHRALDH1A1
SCHEMBL22748689 0.91 TDP1 (0.83) FFAR1CPT2TDP1TSHRALDH1A1
SCHEMBL2496692 0.91 TDP1 (0.83) FFAR1CPT2TDP1KDM4EADRA1A
SCHEMBL6697555 0.91 FFAR1 (0.83) FFAR1CPT2TDP1KDM4EHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023076577-A2 METHODS FOR MODULATING CELL PLURIPOTENCY AND SELF-RENEWAL PROPERTY MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2023-05-04 WO claimed
US-20220218659-A1 PI3K/LYN-ACLY Signaling Inhibition INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER 2022-07-14 US claimed
US-20210137934-A1 METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-05-13 US claimed
US-10512624-B2 Long-chain amphipathic dicarboxylic acids for treatment of diabetes type-1 SYNDROMEX LTD. (IL) 2019-12-24 US claimed
WO-2018170316-A1 METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2018-09-20 WO claimed
US-20180235918-A1 Long-Chain Amphipathic Dicarboxylic Acids for Treatment of Diabetes Type-1 SYNDROMEX LTD. (IL) 2018-08-23 US claimed
EP-1001755-B1 CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYNDROME X LTD (IL) 2011-05-11 EP claimed
US-20100240683-A1 COMBINATION THERAPY, COMPOSITION AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS SYNDROMEX LTD. (IL) 2010-09-23 US claimed
US-20100113599-A1 AMPHIPATHIC CARBOXYLATES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS SYNDROMEX LTD. C/O YISSUM RESEARCH DEVELOPMENT COMPANY, OF (IL) 2010-05-06 US claimed
EP-2131832-A2 COMBINATION THERAPY, COMPOSITION AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS Syndromex Ltd. (IL) 2009-12-16 EP claimed
WO-2008104976-A1 AMPHIPATHIC CARBOXYLATES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS SYNDROMEX LTD. (IL) 2008-09-04 WO claimed
WO-2008104975-A2 COMBINATION THERAPY, COMPOSITION AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS SYNDROMEX LTD. (IL) 2008-09-04 WO claimed
US-20040171585-A1 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them BAR-TANA JACOB (IL) 2004-09-02 US claimed
US-20040171688-A1 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them BAR-TANA JACOB (IL) 2004-09-02 US claimed
US-20020037876-A1 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM 2002-03-28 US claimed
US-4634795-A TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND MATURITY-ONSET DIABETES EPIS S.A. (CH) 1987-01-06 US claimed
EP-0081930-B1 LONG-CHAIN ALPHA, OMEGA-DICARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Epis S.A. (CH) 1986-07-30 EP claimed
EP-0081930-A1 Long-chain alpha, omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them Epis S.A. (CH) 1983-06-22 EP claimed
EP-4281058-B1 FUNCTIONALIZED LONG-CHAIN DICARBOXYLIC ACIDS, AND THEIR USE FOR TREATMENT OF KIDNEY DISEASES ESPERVITA THERAPEUTICS INC (US) 2026-03-18 EP disclosed
EP-0081930-A1 Long-chain alpha, omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them Epis S.A. (CH) 1983-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10512624-B2 Long-chain amphipathic dicarboxylic acids for treatment of diabetes type-1 IAPP, SLC27A1, SLC16A1 FFAR1 91/4885CPT2 84/4885TDP1 1552/4885
US-20100240683-A1 COMBINATION THERAPY, COMPOSITION AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS HMGCR, APOB, CETP FFAR1 71/4885CPT2 45/4885TDP1 2506/4885
US-20100113599-A1 AMPHIPATHIC CARBOXYLATES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS MALT1, TLR9, TLR6 FFAR1 157/4885CPT2 134/4885TDP1 1097/4885
US-20180235918-A1 Long-Chain Amphipathic Dicarboxylic Acids for Treatment of Diabetes Type-1 IAPP, SLC27A1, SLC16A1 FFAR1 91/4885CPT2 84/4885TDP1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.