Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586099 | 0.75 | SLC9A1 (0.38) | SLC9A1LMNATDP1PRMT5TP53 | |
| SCHEMBL20658823 | 0.71 | SLC9A1 (0.52) | SLC9A1LMNATDP1TP53KMT2A | |
| SCHEMBL20658824 | 0.71 | SLC9A1 (0.52) | SLC9A1LMNATDP1TP53KMT2A | |
| SCHEMBL18617433 | 0.65 | ALDH1A1 (0.55) | SLC9A1LMNATDP1TP53KMT2A | |
| SCHEMBL18617435 | 0.62 | ADORA2A (0.38) | LMNAKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18617662 | 0.61 | SLC9A1 (0.48) | SLC9A1LMNATDP1TP53KMT2A | |
| SCHEMBL18617442 | 0.60 | TNF (0.37) | LMNAPRMT5TP53KMT2ATNF | |
| SCHEMBL18617398 | 0.58 | GRM2 (0.43) | SLC9A1LMNAALDH1A1TSHRGRM2 | |
| SCHEMBL20672132 | 0.58 | GRM2 (0.43) | SLC9A1LMNATP53KMT2AALDH1A1 | |
| SCHEMBL20429996 | 0.58 | MPO (0.45) | LMNATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |