Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 16/20 | 0.71 |
| ▸ | BMPR1A | P36894 | 16/20 | 0.71 |
| ▸ | ACVRL1 | P37023 | 16/20 | 0.71 |
| ▸ | ACVR1 | Q04771 | 16/20 | 0.71 |
| ▸ | TGFBR1 | P36897 | 15/20 | 0.71 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | AXL | P30530 | 1/20 | 0.56 |
| ▸ | MERTK | Q12866 | 1/20 | 0.56 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
| ▸ | ATR | Q13535 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779418 | 0.87 | BMPR1B (0.68) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806938 | 0.85 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL517808 | 0.79 | NPC1 (0.72) | — | |
| SCHEMBL18616326 | 0.79 | BMPR1B (0.57) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL13968136 | 0.77 | FYN (0.70) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995196 | 0.77 | BMPR1B (0.71) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL29373251 | 0.77 | BMPR1B (0.71) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30108276 | 0.76 | CNR1 (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL28224390 | 0.76 | CNR1 (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL18617182 | 0.76 | CHEK2 (0.64) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947215-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2021-03-16 | — | — | US | disclosed |
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |
| US-20190119252-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2019-04-25 | — | — | US | disclosed |
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947215-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | BMPR1B 2861/4885BMPR1A 2844/4885ACVRL1 2320/4885 |
| US-20190119252-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | BMPR1B 2861/4885BMPR1A 2844/4885ACVRL1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.