Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 12/20 | 0.68 |
| ▸ | BMPR1A | P36894 | 12/20 | 0.68 |
| ▸ | ACVRL1 | P37023 | 12/20 | 0.68 |
| ▸ | ACVR1 | Q04771 | 12/20 | 0.68 |
| ▸ | TGFBR1 | P36897 | 11/20 | 0.68 |
| ▸ | ATR | Q13535 | 1/20 | 0.55 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.55 |
| ▸ | AXL | P30530 | 3/20 | 0.53 |
| ▸ | MERTK | Q12866 | 3/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18611763 | 0.89 | AXL (0.66) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL18616701 | 0.87 | BMPR1B (0.71) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL18611756 | 0.85 | MERTK (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL18615349 | 0.82 | MERTK (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19807056 | 0.81 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL29370385 | 0.81 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806979 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806978 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL29370244 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19807032 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |