Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14407222 | 0.73 | ADRA2A (0.43) | NR4A2KAT2BTDP1MAPK1 | |
| SCHEMBL20393588 | 0.72 | NR4A2 (0.34) | NR4A2KAT2B | |
| SCHEMBL27401613 | 0.71 | ALPL (0.37) | NR4A2KAT2B | |
| SCHEMBL9250961 | 0.71 | AHR (0.39) | GAATDP1MAPK1 | |
| SCHEMBL4305366 | 0.69 | CYP3A4 (0.46) | NR4A2GAATDP1MAPK1 | |
| SCHEMBL30374051 | 0.69 | NR4A2 (0.38) | NR4A2GAA | |
| SCHEMBL20096882 | 0.68 | GAA (0.40) | NR4A2KAT2BGAATDP1GLP1R | |
| SCHEMBL2157691 | 0.68 | CA1 (0.55) | NR4A2GAA | |
| SCHEMBL8359924 | 0.68 | RAPGEF4 (0.47) | NR4A2GAATDP1 | |
| SCHEMBL20655526 | 0.68 | NPC1 (0.47) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017038838-A1 | NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-03-09 | — | — | WO | disclosed |