Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 18/20 | 0.55 |
| ▸ | TPO | P07202 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | EPX | P11678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18618819 | 0.94 | MPO (0.51) | MPOTPOCYP3A4EPX | |
| SCHEMBL18618875 | 0.86 | MPO (0.55) | MPOTPOCYP3A4EPX | |
| SCHEMBL18620321 | 0.85 | MPO (0.56) | MPOTPOCYP3A4EPX | |
| SCHEMBL18621228 | 0.83 | MPO (0.55) | MPOTPOCYP3A4EPX | |
| SCHEMBL18620320 | 0.82 | MPO (0.59) | MPOTPOCYP3A4EPX | |
| SCHEMBL18620322 | 0.82 | MPO (0.59) | MPOCYP3A4 | |
| SCHEMBL18618817 | 0.81 | MPO (0.67) | MPOTPOCYP3A4 | |
| SCHEMBL18620054 | 0.81 | MPO (0.60) | MPOCYP3A4 | |
| SCHEMBL18620324 | 0.80 | MPO (0.53) | MPOTPOCYP3A4EPX | |
| SCHEMBL18618945 | 0.80 | RAB9A (0.41) | MPOTPOCYP3A4EPX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040451-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |