Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795052 | 0.90 | CYP3A4 (0.53) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL24795050 | 0.88 | CYP3A4 (0.52) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL28690191 | 0.84 | HPRT1 (0.50) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL29452873 | 0.80 | CYP3A4 (0.75) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL2386087 | 0.80 | CYP3A4 (0.75) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL33943 | 0.79 | CYP3A4 (0.86) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL30424189 | 0.79 | PTK2 (0.64) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL18623483 | 0.79 | PTK2 (0.64) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL23665415 | 0.77 | CYP3A4 (0.41) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 | |
| SCHEMBL439013 | 0.76 | CYP3A4 (0.80) | CYP3A4TSHRMAPK1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073364-A1 | COMPOSITIONS AND METHODS COMPRISING CONDUCTIVE METAL ORGANIC FRAMEWORKS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073364-A1 | COMPOSITIONS AND METHODS COMPRISING CONDUCTIVE METAL ORGANIC FRAMEWORKS AND USES THEREOF | ILK, AOC1, OCIAD2 | CYP3A4 3831/4885TSHR 4769/4885MAPK1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.