Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623959 | 0.83 | MAPT (0.38) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL18623953 | 0.80 | SMN1; SMN2 (0.35) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL18623952 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL18179775 | 0.70 | MEN1 (0.43) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL21396616 | 0.70 | KDM1A (0.38) | ALDH1A1MAPTGAANPSR1KDM4E | |
| SCHEMBL24591429 | 0.70 | SLC2A1 (0.35) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL18606132 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL18623951 | 0.67 | GAA (0.33) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 | |
| SCHEMBL24591452 | 0.67 | S100B (0.40) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL29707447 | 0.65 | MEN1 (0.36) | ALDH1A1MAPTGAANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981934-B2 | Enzyme-specific fluorescent compound capable of being retained in cells | THE UNIVERSITY OF TOKYO (JP) | 2018-05-29 | — | — | US | disclosed |
| US-9981934-B2 | Enzyme-specific fluorescent compound capable of being retained in cells | THE UNIVERSITY OF TOKYO (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170073321-A1 | ENZYME-SPECIFIC FLUORESCENT COMPOUND CAPABLE OF BEING RETAINED IN CELLS | THE UNIVERSITY OF TOKYO (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170073321-A1 | ENZYME-SPECIFIC FLUORESCENT COMPOUND CAPABLE OF BEING RETAINED IN CELLS | THE UNIVERSITY OF TOKYO (JP) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073321-A1 | ENZYME-SPECIFIC FLUORESCENT COMPOUND CAPABLE OF BEING RETAINED IN CELLS | GLB1, GLA, GUSB | ALDH1A1 161/4885MAPT 3579/4885GAA 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.